Friday, August 5, 2016
Tuesday, August 2, 2016
Tuesday, July 12, 2016
Central Giant-Cell Granuloma
Central
Giant-Cell Granuloma
Giant
cell lesions of the jaws are more frequent in first two decade of life and are
more prevalent in female patients 2:1
Although other lesions containing giant cells do occur in other bones of the body, they are much less frequent and are generally felt to be variants of other tumors, most often a low-grade osteosarcoma.
Diagnosis of central giant cell
granuloma is made histologically from an incisional biopsy.
Similar histological appearances
are seen in the following lesions, which must often be differentiated:
- The brown tumor of
hyperparathyroidism.
- The aneurysmal bone cyst.
- Cherubism.
Conventional management is surgical
and consists of:
1. Enucleation and curettage.
Despite this, a recurrence rate of 15-20% is often quoted, and in these cases
treatment may need to be more aggressive and may need to consist of an “en
bloc” resection.
2. Intralesional steroid injections protocol is a 50/50 mixture of 2%
lidocaine with 1:100,000 epinephrine with triamcinolone (Kenalog®)
Experience
with this technique is limited. In the hands of those who use this technique on
a regular basis, it appears that it is successful in around 50% of cases
3. Calcitonin injections
In
the United States only salmon calcitonin is available, and although it is more
potent than human calcitonin, antibody formation can limit its effectiveness. Results
from the use of calcitonin have shown fairly high success rates.
Treatment with alpha interferon
Based
on the assumption that this lesion may be vascular in origin, subcutaneous
alpha interferon has been used in the treatment of this lesion. It is given for
its anti-angiogenic effects, though there is little evidence that the lesion is
vascular in origin. The treatment has shown some success, but its use is
limited by its side effects.
Below
see a case treated with both Intralesional
steroid injections and Calcitonin on a 12 year old with a 5 year follow up with
no recurrence.
At presentation
6 months post treatment
1 year post treatment
4 year post treatment
5 year post treatment
Friday, June 17, 2016
Mesiodentes
A mesiodent is an extra tooth in the maxillary anterior incisor
region. Mesiodentes are the most common supernumerary teeth,
occurring in 0.15% to 1.9% of the population. The etiology of mesiodens is unclear, but is twice prevalent in
males (possibly an autosomal recessive gene), and there is a familial trait. Proliferation
of the dental lamina and genetic factors have been implicated. Mesiodentes can
cause delayed or ectopic eruption of the permanent incisors, which can further
alter occlusion and appearance.
Mesiodens sometimes
interfere with eruption of permanent teeth and cause other alignment problems
with the existing teeth. Only a small portion of supernumerary teeth eventually
erupts.
To prevent additional
damage such as misalignment and delayed eruption of the permanent central
incisors early intervention is suggested. Usually it is preferred to wait until
the root of the central and the lateral teeth are completely formed before
mesiodents are removed.
Mesiodens have been
found in certain syndromes such as cleft lip and palate, cleidocranial
dysostosis, and Gardner's syndrome. Supernumerary teeth in general have
associations with Ehler-Danlos syndrome, Apert syndrome, and Down's syndrome as
well.
The concerns associated
with mesiodens are listed below and removal is often needed
1. Delayed eruption of
permanent teeth
2. Cyst formation
3. Crowding
4. Diastemas
5. Resorption of the
roots of adjacent teeth
6. Eruption of mesiodens in to the nasal cavity..
Below see two cases that show the mesiodents erupting in to the nasal cavity.
Friday, June 10, 2016
Glubomaxillary cyst or Periapical cyst?
Globulomaxillary
cyst has been considered to be a developmental cyst that arises from entrapped
nonodontogenic epithelium in the globulomaxillary suture. In recent years
existence and histogenesis of this lesion has been disputed. It had been argued
that the anterior maxilla was formed by merging of growth centers rather than
fusion of facial processes and therefore, ectodermal entrapment was ruled out. Recent
embryologic studies have demonstrated that Fusion of facial processes does
occur, and epithelium is entrapped in areas that later will lie between the
maxillary lateral incisors and canines. At the present Globumaxillary cyst has
been removed from WHO classification of non odontogenic cyst and some argue
that it needs to be reinstated as a developmental non odontogenic cyst.
Below see a case which could potentially be
argued both ways. 40 year old male presented with swelling of the space between
maxillary left canine and lateral incisor. Patient had been treated with a root
canal treatment years go on teeth #8, 9, and 10 and does not recall why. He
denies history of trauma to the anterior maxilla. Panoramic
x ray disclosed potentially an endodontic
lesion in apex of #10 and cystic lesion that has resulted in root divergence in
the area of tooth #10 and 11. Tooth #11 has tested vital and has been ruled out
as a potential source of the lesion. Pathology was consistent with both periapical lesion
arising from tooth#10 and a non odontogenic cyst.
Thursday, June 9, 2016
Friday, June 3, 2016
BIlateral Mandibular swelling
34 year old female was referred from her dentist for mandibular swelling. Patient was complaining of lower jaw pain and swelling of 2 days duration and has been febrile for the past week. Health questionnaire was also negative for any systemic disease and patient claimed no past surgical history. Examination of the face was consistent with lower facial swelling not extending beyond the lower mandibular border and skin was flushed and warm to palpation. Bilateral mandibular body and chin and all lower teeth were tender to palpation and all lower teeth have plus 2 mobility. No decay was observed on any of the lower teeth. Panoramic x-ray was taken and no odontogenic source for the infection was identified. Periodontal exam was also negative. A Cone beam CT was taken and a silicone mandibular implant was identified spanning from right mandibular body to the left. The implant had resorbed the cortical bone. Upon further questioning about past surgical history patient said she was embarrassed and did not disclosed the implant placement since her husband might find out!!
IV antibiotic was given and the implant was removed under general anesthesia.
IV antibiotic was given and the implant was removed under general anesthesia.
Friday, May 13, 2016
Odontoma
Most common odontogenic tumor is an Odontoma. Odontomas are considered to be hamartomas rather than neoplasms. These lesions are composed of tissues native to teeth: enamel, dentin, cementum and pulp tissue.
Odontomas are classified based on their gross and radiographic features into compound (small tooth like structures) or complex (a conglomeration of dentin, enamel and cementum) Clinical symptoms are uncommon, however, an affected patient may present when a permanent tooth or multiple teeth that fail to erupt.
Usually, odontomas can be confidently subclassified based on the Xray appearance. Compound odontomas appear as a collection of small teeth. Complex odontomas appear as a radioopaque mass which may result in a wider differential diagnosis.
Below is a case of a 16 year old male who was referred for removal of his wisdom teeth. Panoramic x ray was consistent with compound odontoma. CT scan was obtained to assess best access point to remove the lesion.
Traumatic Bone Cyst
The traumatic bone cyst is an uncommon non epithelial lined cavity of the jaws. The cyst is mainly diagnosed in young patients most frequently in their teen. Most of these lesions are located in the mandible. These lesions are asymptomatic in the most of cases and are often discovered on routine dental X-rays. Since epithelial lining is non existent, microscopic diagnosis may be difficult.
Below see a Ct scan of a 15 Year old male athelete presenting to our office with large cystic lesion of left mandibular body which was discovered on panoramic x ray when he was consulting an orthodontist.
At surgery, we discovered a large cystic lesion devoid of any epithelium. Scrapings of the cyst was consistent with diagnosis of Traumatic bone cyst per pathologist.
The recommended treatment for this lesion is surgical exploration followed by curettage of the bony walls.
The surgical exploration serves as both a diagnostic and as definitive therapy by producing bleeding in the cavity. Blood clot formation in the cavity is eventually replaced by bone.
Below see a Ct scan of a 15 Year old male athelete presenting to our office with large cystic lesion of left mandibular body which was discovered on panoramic x ray when he was consulting an orthodontist.
At surgery, we discovered a large cystic lesion devoid of any epithelium. Scrapings of the cyst was consistent with diagnosis of Traumatic bone cyst per pathologist.
The recommended treatment for this lesion is surgical exploration followed by curettage of the bony walls.
The surgical exploration serves as both a diagnostic and as definitive therapy by producing bleeding in the cavity. Blood clot formation in the cavity is eventually replaced by bone.
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